I've just released the new 22.214.171.124 build of wxPython. This release has had some bugs fixed, some minor patches applied, and also incorporates the Google Summer of Code 2007 version of XRCed, and adds the Editra source code editor. More details can be found in the changes list. wxPython source and binaries for Windows, Mac OS X and Fedora can be downloaded from the download page. Binaries for Debian and Ubuntu i386 and amd64 architectures are available in the wxWidgets APT repository, see this wiki page for details.
NOTE: On Mac OS X 10.5 (Leopard) the Python 2.5 binaries of wxPython expect to be used with the user-installed version of MacPython, not the Apple installed version. A fix for this issue is being worked on for the next release. In the meantime you can either install MacPython 2.5.1 and adjust your paths so that that Python is used, or you can stick with Apple's Python and the wxPython 126.96.36.199 that comes with Leopard.